|Fetus in First Trimester|
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- Chromosomal abnormalities (common cause)
- Abnormalities in the uterine tract, such as fibroids
- Hormonal problems, such as not having enough progesterone, a female hormone needed to support pregnancy
- Factors related to the immune system, such as blood-clotting problems or rejection of the fetus
- Smoking , drinking alcohol , or using drugs during pregnancy
- Certain medications
- Exposure to certain environmental toxins
- Autoimmune disorders, such as systemic lupus erythematosus
- High-dose radiation therapy on the ovaries, uterus, or the pituitary gland during treatment of childhood cancers
- Vaginal bleeding
- Pink or brown discharge
- Passing the fetus, placenta, and surrounding membranes through the vagina
- Chromosome problem in one member of the couple
- Uterine abnormalities
- Hormone problems
- Immune system problems
- Unknown causes
- Ultrasound —to assess the health of the fetus
- Blood tests—to check the exact amount of the hormone (called human chorionic gonadotropin or hCG) important to sustain an early pregnancy
- Examination of the tissue that has passed through the vagina
- Blood tests—to check for a chromosomal error in the man or the woman or to check hormone and antibody levels
- Endometrial biopsy —to check the uterine lining to see if it can support a pregnancy
- Is your diet ready to support another pregnancy?
- Are there habits you should change prior to another pregnancy?
- What medications are you taking and will they affect a pregnancy?
- How is your health?
- Are there issues you should resolve before trying another pregnancy?
Medications such as:
- Antibiotics to treat related infections
- Hormone (progesterone) supplements
- Aspirin and other medications to treat blood-clotting problems
Surgery for uterine problems such as:
- Uterine fibroids
- Septate uterus (tissue in the center of the uterus)
- Incompetent (weakened) cervix
The American Congress of Obstetricians and Gynecologists http://www.acog.org
March of Dimes http://www.marchofdimes.com
The Society of Obstetricians and Gynaecologists of Canada http://www.sogc.org
Women's Health Matters http://www.womenshealthmatters.ca
First trimester pregnancy loss. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated May 29, 2015. Accessed October 7, 2015.
Miscarriage. American Pregnancy Association website. Available at: http://americanpregnancy.org/pregnancycomplications/miscarriage.html. Updated August 2015. Accessed October 7, 2015.
Miscarriage. March of Dimes website. Available at: http://www.marchofdimes.com/loss/miscarriage.aspx. Updated July 2012. Accessed October 7, 2015.
Second trimester pregnancy loss. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated August 10, 2015. Accessed October 7, 2015.
Recurrent pregnancy loss. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated August 10, 2015. Accessed October 7, 2015.
12/2/2008 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Winther JF, Boice JD Jr, Svendsen AL, Frederiksen K, Stovall M, Olsen JH. Spontaneous abortion in a Danish population-based cohort of childhood cancer survivors. J Clin Oncol. 2008;26:4340-4346.
4/16/2009 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Bhattacharya S, Townend J, Shetty A, Campbell D, Bhattacharya S. Does miscarriage in an initial pregnancy lead to adverse obstetric and perinatal outcomes in the next continuing pregnancy? BJOG. 2008;115:1623-1629.
6/25/2010 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Nakhai-Pour HR, Broy P, Bérard A. Use of antidepressants during pregnancy and the risk of spontaneous abortion. CMAJ. 2010 May 31.
- Reviewer: Andrea Chisholm, MD
- Review Date: 09/2015 -
- Update Date: 09/30/2013 -